IndraLab

Statements


SMAD3 phosphorylated on T179 is active. 2 / 2
2 |

"As receptor-activated smads form transcriptional complexes, they are phosphorylated at an interdomain linker region by cdk8 and cdk9, which are components of transcriptional mediator and elongation complexes. These phosphorylations promote smad transcriptional action"

"As receptor-activated smads form transcriptional complexes, they are phosphorylated at an interdomain linker region by cdk8 and cdk9, which are components of transcriptional mediator and elongation complexes. These phosphorylations promote smad transcriptional action"