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BAP1 leads to the deubiquitination of PPARGC1A. 1 / 1

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"However, this is unlikely to account for the stabilization of PGC-1alpha by OGT because 1) the S333A mutation, which bypasses the effects of O GlcNAcylation on the proteasome, increases PGC-1alpha ubiquitination and decreases its stability, 2) HCF-1 and BAP1 have no effect on proteasome function or global ubiquitination (XREF_FIG and data not shown), but can decrease PGC-1alpha ubiquitination and increase its stability."

22883232

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IndraLab

Statements

BAP1 leads to the deubiquitination of PPARGC1A. 1 / 1

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