Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BAP1 leads to the deubiquitination of PPARGC1A. 1 / 1

| 1

➶

reach

"However, this is unlikely to account for the stabilization of PGC-1alpha by OGT because 1) the S333A mutation, which bypasses the effects of O GlcNAcylation on the proteasome, increases PGC-1alpha ubiquitination and decreases its stability, 2) HCF-1 and BAP1 have no effect on proteasome function or global ubiquitination (XREF_FIG and data not shown), but can decrease PGC-1alpha ubiquitination and increase its stability."

22883232

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...