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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ERK binds RAS, SOS1, and GRB2. 1 / 1

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"Previous reports showed that pDOK3 associates with the cytosolic adaptor protein Grb2 (growth factor receptor–bound protein 2) and the Ras GEF Sos1 (son of sevenless 1) to prevent activation of the Ras-ERK pathway downstream of protein-tyrosine kinases in transfected human embryonic kidney (HEK) 293T cells ( xref )."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...