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SJB3-019A inhibits USP1. 3 / 3
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eidos
"Similarly , pharmacological inhibition of USP1 by SJB3-019A significantly repressed cell proliferation and triggered B-ALL cell apoptosis ."

reach
"Furthermore, our data indicates that SJB3-019A (XREF_SUPPLEMENTARY), which has previously been shown to inhibit USP1 in leukemic cells 47, inhibits USP8 more strongly (IC 50 0.21 muM) than USP1 (IC 50 1.69 muM) but in addition also significantly inhibited several other DUBs tested."

reach
"Similarly, pharmacological inhibition of USP1 by SJB3-019A significantly repressed cell proliferation and triggered B-ALL cell apoptosis."