IndraLab

Statements


Modified JAK2 leads to the phosphorylation of JAK2 on tyrosine. 3 / 3
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"However, expression of wild-type Jak2 did not increase the relative amount of Jak2 tyrosine phosphorylation as compared to nontransfected cells (lanes 1 and 2)."

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"Relative Jak2 tyrosine phosphorylation could be restored by the overexpression of wild-type Jak2 (lane 5), whereas combinatory AG490 treatment and Jak2dn expression further decreased Jak2 tyrosine pho[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"This observation indicates that overexpression of Jak2 is sufficient to induce Jak2 tyrosine phosphorylation in Ba/F3-NA cells."