IndraLab

Statements


IFNG activates USP18. 3 / 3
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"The low-level induction of USP18 by IFN-gamma was not sufficient to attenuate (peg) IFN-alpha-mediated signaling."

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"The novel finding in this study is the discovery that the ubiquitin specific peptidase USP18 can be induced by IFN-gamma in tumor cells and plays important roles in inhibiting tumorigenesis and antitumor immunity."

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"92 Hong et al. 93 found that IFN-gamma can induce USP18 in tumor cells and that this protein plays an important role in inhibiting tumorigenesis and maintaining antitumor immunity."