IndraLab

Statements

PDPK1 phosphorylated on S241 is active. 5 / 5
3 2 |
biopax:pid
No evidence text available
signor
"In terms of the modulation of PDK1 activity by reversible phosphorylation, five pS sites have been identified on PDK1 in vivo, but only one of these sites, Ser-241 in the activation loop of PDK1, is essential for activity. It seems likely that PDK1 autophosphorylates itself on this residue."
11481331
biopax:pid
No evidence text available
10856237
biopax:pid
No evidence text available
10480933
signor
"Pdk1 is itself phosphorylated in vivo and whether phosphorylation plays a role in regulating its activity/ phosphorylation of ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1"
10455013