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NMRAL1 bound to IKBKG inhibits USP7. 1 / 1

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"NFkappaB can be directly deubiquitinated by HAUSP 87 or can be indirectly regulated by deubiquitination of its upstream factors, such as TRAF6, 24 NEMO (IKK-gamma) XREF_BIBR, XREF_BIBR (HSCARG interacts with NEMO to suppress its polyubiquitination by recruiting HAUSP 91), NIMA (Never In Mitosis Gene A)-related kinase 2 (Nek2), a centrosomal serine/threonine kinase (HAUSP stabilizes Nek2 leading to activation of NFkappaB pathway in multiple myeloma)."

29967688

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IndraLab

Statements

NMRAL1 bound to IKBKG inhibits USP7. 1 / 1

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