IndraLab

Statements



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"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion 57 ."

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"We believe that UCH37 could be a good diagnostic and therapeutic target for controlling HCC recurrence, and further investigations in this field are needed.This study provided evidence for the first t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In vitro, we discovered that UCH37 could promote cell migration and invasion."

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"Intriguingly, knock-down of PRP19 reduced the capability of cell migration and invasion, compare with the control cells, suggesting that UCH37 exerted its effects at least in part by deubiquitinating [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"UCH37-knockdown reduced the cell capability to invade extracellular matrix (Huh7-pLKO.1, 23 +/- 3 vs. Huh7-shUCH37, 3 +/- 1, p < 0.05), whereas forced expression of UCH37 increased invasiveness (L02-p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion ."

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"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma (HCC) XREF_BIBR."

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"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma ( HCC ) 12 ."

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"Furthermore, we discovered that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, an essential RNA splicing factor.Tumor specimens used [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

eidos
"UCHL5 is also overexpressed in hepatocellular carcinoma , and was shown to promote cell migration and invasion 57 ."

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"All of the evidences suggest that the up-regulation of UCH37 may play an important role in oncogenesis through promoting some proto-oncogenes ' expression and stem cell like characteristics in the cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Collectively, this study demonstrated that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, and suggested that UCH37 could be a novel predictor for HCC recurrence after curative resection."