IndraLab

Statements

reach
"We believe that UCH37 could be a good diagnostic and therapeutic target for controlling HCC recurrence, and further investigations in this field are needed.This study provided evidence for the first t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Our group found that UCH37, a novel predictor for HCC recurrence, promoted cell migration and invasion via up-regulated PRP19 (pre-mRNA processing factor 19) [75] ."
26193663
reach
"Furthermore, we discovered that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, an essential RNA splicing factor.Tumor specimens used [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"UCH37-knockdown reduced the cell capability to invade extracellular matrix (Huh7-pLKO.1, 23 +/- 3 vs. Huh7-shUCH37, 3 +/- 1, p < 0.05), whereas forced expression of UCH37 increased invasiveness (L02-p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Correspondingly, UCHL5 could promote cell invasion and migration through regulating FASN (Fig. 5F, G)."
39075049
reach
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma (HCC) XREF_BIBR."
33046988
reach
"All of the evidences suggest that the up-regulation of UCH37 may play an important role in oncogenesis through promoting some proto-oncogenes ' expression and stem cell like characteristics in the cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Intriguingly, knock-down of PRP19 reduced the capability of cell migration and invasion, compare with the control cells, suggesting that UCH37 exerted its effects at least in part by deubiquitinating [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"UCHL5 inhibition negatively regulated TGF-beta1-induced Smad2 activation, decreasing extravillous trophoblast invasiveness."
37762005
eidos
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma ( HCC ) 12 ."
33046988
reach
"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion ."
28959952