IndraLab

Statements

USP1 binds ESR1. 5 / 5
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"The endogenous immuno-precipitation showed that USP1 could interact with ERα in MCF-7 cells (Fig. xref C)."
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"Immuno-precipitation assays indicate that USP1 associates with ERα and promotes its stability possibly via inhibiting ERα K48-linked poly-ubiquitination."
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"Since USP1 could associate with ERα in breast cancer cells, we further investigate the biological effect of such interaction."
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"USP1 associates with ERα and regulates ERα stability."
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"The mechanistic experiments revealed that USP1 associated with ERα and increased ERα stability via prohibiting ERα K48-linked poly-ubiquitination in breast cancer cells (Fig. xref C)."
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