IndraLab

Statements


USP14 inhibits K48-. 2 / 2
| 2

reach
"In the present study, we provided the evidence that both K48- and K63-linked polyubiquitination on HIF1-α were significantly reduced by overexpression of USP14, suggesting that USP14 is involved in the maintenance of HIF1-α stability by triggering K48- and K63-linked deubiquitination on HIF1-α via its deubiquitination activity."

reach
"Our results demonstrated that K48- and K63- linked ubiquitination on HIF1-α were substantially decreased by the overexpression of USP14 (Fig. 3F)."