IndraLab
Statements
reach
"With anti-Ubi N antibody, we show that altering ataxin-3 levels did not affect the levels of ubiquitin moieties expressed in cells (XREF_FIG F, comparing input lanes 1 and 7, and lanes 4 and 10) or pulled down in the aggregates (XREF_FIG F, comparing lanes 3 and 9 and lanes 6 and 12), suggesting that ataxin-3 knockdown did not reduce the total level of ubiquitin expressed in cells or the ubiquitin associated with protein aggregates but only specifically reduced the amount of unanchored ubiquitin C termini in protein aggregates."