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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL5 increases the amount of IL1B. 1 / 1

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"Whether USP7 and USP47 directly interact with NLRP3 receptor or with other inflammasome component was not investigated.Enzymatic activity of UCHL5 (from the ubiquitin C-terminal hydrolase family) is also increased after Salmonella enterica serovar Typhimurium infection, and UCHL5 silencing leads to impaired release of IL-1b after infection [57] ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...