IndraLab

Statements


FSD1 decreases the amount of HCN4. 2 / 2
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"MiR-1 and -133 exert inhibitory effects upon HCN2, while miR-1 is also able to downregulate HCN4 expression."

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"37 Relevant to the present discussion, down-regulation of miR-1 and miR-133 have been associated with increased protein levels of HCN2 and HCN4 in hypertrophic hearts, whereas transfection of miR-1 and miR-133 into angiotensin II stimulated neonatal cardiac myocytes prevented overexpression of HCN2 and HCN4."