IndraLab

Statements


Charge activates ZUP1. 1 / 1
| 1

eidos
"Indeed , mutating Ile847 to Ala , which conserves its apolar properties , has a significant but mild effect on DUB activity , both in vitro and in vivo , whereas addition of a negative charge in this region ( mutation I847D ) drastically decreased DUB activity ( 28 , 34 ) ."