IndraLab

Statements

KCNMA1 activates nitric oxide. 3 / 3
| 3
reach
"Stimulation of BK channel activity by the nitric oxide (NO)/soluble guanylate cyclase (sGC)/cGMP-dependent protein kinase (PKG) pathway, which is important in mediating the effects of endothelial dependent vasodilators, is not thought to be involved in modulating the myogenic response of small resistance arteries during basal tone because there is no evidence for pressure induced release of NO from the endothelium XREF_BIBR - XREF_BIBR."
27729550
reach
"Recently, it has been demonstrated that the BK channel opener CGS7184 increases the biosynthesis of NO in an endothelial cell line, causes the vasodilatation of the rat aortic ring and increases coron[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
20178786
reach
"In nerve terminals of the posterior pituitary, NO increases BK channel conductance, generating spike after hyperpolarization and also Na + channels recovery from inactivation, so reducing action potential failures."
27872689