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ATXN3 deubiquitinates EIF4G2. 1 / 1

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"We demonstrate that atx3 transiently associates with the ER membrane via p97 and the recently identified Derlin-VIMP complex, and its release from the membrane appears to be governed by both the p97 ATPase cycle and its own deubiquitinating activity.| We present evidence that atx3 may promote p97-associated deubiquitination to facilitate the transfer of polypeptides from p97 to the proteasome."

17000876

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ATXN3 deubiquitinates EIF4G2. 1 / 1

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