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USP18 inhibits Feedback. 1 / 1

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"However , IFN - s are probably not the drivers of ISG induction because IFN - signaling is subject to a strong negative feedback inhibition by USP18 that would prevent long-lasting activation of ISGs ( Malakhova et al ., 2006 ; Sarasin-Filipowicz et al ., 2009 ) ."

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USP18 inhibits Feedback. 1 / 1

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