IndraLab

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PSMD14 deubiquitinates ACVR1. 2 / 3
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"In agreement with this, in cancer cells PSMD14 deubiquitinates and stabilizes another member of the family, the BMP receptor ALK2 [ 43 ]."

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"In colorectal cancer, PSMD14 mediates the deubiquitination of ALK2 to enhance its stability and activate the BMP6 signaling pathway."