IndraLab

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"To determine whether the up-regulation of A20 was associated with the down-regulation of IRAK1, HMC cells were transfected with A20, and IRAK1 protein levels were detected in three mock-transfected and three A20 over-expression clones."

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sparser
"Thus, deficient LPS-induced activation of IRAK4 and TAK1, K63-linked polyubiquitination of IRAK1 and TRAF6, and disrupted IRAK1-TRAF6 and IRAK1-IKKγ assembly associated with increased A20 expression and A20-IRAK1 interactions are new determinants of endotoxin tolerance."