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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

RASSF1A promoters methylates CDKN2A. 1 / 1

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reach

"Furthermore, since 5mTHF is involved in the supply of methyl groups to the remethylation cycle in which DNA is a terminal acceptor, FA may alter BC risk through altered epigenetic regulation of tumour suppressor genes as BC can involve hypermethylation of P16INK4a, BRCA1, BRCA2, oestrogen receptor (ER)-alpha, retinoic acid receptor-beta2, APC, and RASSF1A promoters leading to lower transcription and to impaired DNA repair."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...