IndraLab

Statements

USP22 binds COPS5. 13 / 16
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"Moreover, USP22 also interacted with CSN5 and stabilized CSN5 through deubiquitination."
32665011
sparser
"USP22 also interacted with CSN5 and kept its stability via deubiquitination."
37215134
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"Moreover, USP22 also interacted with CSN5 and stabilized CSN5 through deubiquitination."
32665011
reach
"USP22, a ubiquitin carboxyl-terminal hydrolase, interacted with JAB1 and stabilized JAB1 through deubiquitination (Wang et al. 2020b)."
37365502
sparser
"On the other hand, USP22 interacts with CSN5 and deubiquitinates it, thereby facilitating the interaction between PD-L1 and CSN5 ( xref )."
37415977
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"USP22 interacted with CSN5 and deubiquitinated CSN5."
32665011
sparser
"Additionally, USP22 forms a complex with CSN5, maintaining its stability via deubiquitination."
38638430
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"Since CSN5 bound to PD-L1 [ xref ], we wondered if USP22 interacted with CSN5 physically."
32665011
reach
"Additionally, USP22 forms a complex with CSN5, maintaining its stability via deubiquitination."
38638430
sparser
"As expected, USP22 interacted with CSN5 exogenously and endogenously (Fig.  xref a, Fig. xref b)."
32665011
sparser
"Moreover, USP22 can bind to CSN5 to deubiquitinate it, inhibit its degradation, and ultimately prolong the half-life of PD-L1 xref , xref ."
39525573
sparser
"Mechanistically USP22 interacts with CSN5 and stabilizes CSN5 in part through deubiquitination, which further inhibits the degradation of PD-L1 in cells [ xref ]."
33831533
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"Taken together, USP22 interacted with CSN5 and stabilized CSN5 protein through its deubiquitination activity."
32665011