IndraLab

Statements

NPM1 is phosphorylated on S70. 37 / 37
33 | 3 1
hprd
No evidence text available
18691976
rlimsp
"Recent studies demonstrated that deregulated phosphorylation at certain sites (Ser10 and Ser70) of NPM enhanced cell transformation and leukemic blasts in NOD/SCID mice [11]."
26536659
hprd
No evidence text available
18767875
hprd
No evidence text available
17924679
hprd
No evidence text available
18767875
hprd
No evidence text available
19007248
hprd
No evidence text available
19007248
hprd
No evidence text available
17287340
hprd
No evidence text available
19415658
hprd
No evidence text available
19415658
hprd
No evidence text available
20068231
hprd
No evidence text available
20230923
hprd
No evidence text available
18691976
hprd
No evidence text available
17924679
hprd
No evidence text available
16565220
hprd
No evidence text available
19651622
hprd
No evidence text available
20230923
hprd
No evidence text available
19651622
hprd
No evidence text available
20230923
hprd
No evidence text available
19007248
hprd
No evidence text available
20068231
sparser
"CDK1 activity and the proper interaction between CDK1 and Cdc25C is promoted by the phosphorylation of nucleophosmin at both Ser10 and Ser70 [971] ."
22743550
hprd
No evidence text available
20068231
hprd
No evidence text available
17287340
hprd
No evidence text available
18767875
sparser
"Further analysis revealed that phosphorylation of NPM at both Ser10 and Ser70 was required for proper interaction between Cdk1 and Cdc25C. Moreover, NPM-EE directly bound to Cdc25C and prevented phosphorylation of Cdc25C at Ser216 during mitosis."
19933706
hprd
No evidence text available
17287340
hprd
No evidence text available
18691976
hprd
No evidence text available
19651622
hprd
No evidence text available
17924679
hprd
No evidence text available
17322306
hprd
No evidence text available
16565220
sparser
"Regarding trans -effects of these deletions, higher phosphorylation of HDAC1 at S406, S410, and S421, and of SMARCA4 at S613 were associated with SMAD4 deletions, while CDKN2A deletions were associated with higher phosphorylation of NPM1 at S70 and S214 ( xref )."
34534465
hprd
No evidence text available
18452278
hprd
No evidence text available
18452278
hprd
No evidence text available
19415658
hprd
No evidence text available
18452278