IndraLab

Statements

CDK4 phosphorylates RB1 on S807. 6 / 6
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biopax:phosphositeplus
No evidence text available
reach
"CDK4 phosphorylates S807/S811 on Rb, and this partial phosphorylation is needed for CDK2 phosphorylation ."
35188696
biopax:netpath
No evidence text available
14627988
reach
"Phosphorylation of Rb at serine 807/811 is mediated primarily by cyclinD and CDK4 (Knudson and Wang, 1996)."
12591091
reach
"Retinoblastoma protein (pRb) phosphorylation on Ser807 and Ser811 (p-pRb) by CDK4 and CDK6 and D-type cyclins, represents the first step of cell cycle progression after cell activation."
25675863
reach
"The resulting loss of CDK4 function prevented downstream Rb phosphorylation at S780 and S807/811, leading to cell cycle arrest by failure at the S-phase checkpoint."
36484997