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USP15 inhibits interaction RIG-I IPS-1 DUB activity-independent manner. 3 / 3
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eidos
"These results suggest that USP15 sequesters the interaction between RIG-I and IPS-1 in a DUB activity-independent manner by acting as a competitor of IPS-1 for RIG-I binding , resulting in the inhibition of both IPS-1 activation and subsequent type I IFN production ."

eidos
"USP15 sequesters the interaction between RIG-I and IPS-1 in a DUB activity-independent manner ."

eidos
"Scientific RepoRts | 5:11220 | DOi : 10.1038 / srep11220 USP15 sequesters the interaction between RIG-I and IPS-1 in a DUB activity-independent manner ."