IndraLab
Statements
reach
"To determine whether IKKalpha phosphorylates NPM, we used different NPM deletion and mutation forms as kinase substrates and found that IKKalpha phosphorylated the amino acid (aa) 119-195 region, which contains five serine sites, but a kinase-dead IKKalpha mutant (IKKalpha-KA) did not phosphorylate NPM (XREF_FIG; XREF_SUPPLEMENTARY)."