IndraLab

Statements


| 4

sparser
"USP14 is one of the three proteasome-associated deubiquitinase (DUB) enzymes, USP14 and UCHL5 being the two that are associated reversibly with the proteasome [ xref ]."

sparser
"USP14 and UCHL5 associate with the proteasome through different ubiquitin receptors, USP14 to Rpn1 at the base of the 19S RP and UCHL5 to Rpn13/ADRM1 at the top of the 19S RP [ xref ] ( xref )."

sparser
"Later, it was determined that b-AP15 targeted the proteasome-bound USP14 and UCHL5, which belong to the USP and UCH families, respectively [ xref ]."

sparser
"The HA-UbVS pull-down also isolated known DUBs interactors ( xref ) such as proteasome subunits, consistent with the known interaction of UCHL5 and USP14 with the proteasome ( xref )."