IndraLab

Statements

USP1 activates Neoplasms. 3 / 3
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"More importantly, USP1 inhibition recedes cell proliferation and clone formation in PDAC cells and attenuates pancreas tumor growth in an orthotopic transplanted mice model."
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"In vivo, USP1 silencing repressed the volume and weight of CRC tumor in the nude mice."
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"Co-treatment with USP1 and MAST1 inhibitors abrogated tumor growth and synergistically enhanced cisplatin efficacy, suggesting a novel alternative combinatorial therapeutic strategy that could further improve MAST1-based therapy in patients with cisplatin-resistant tumors."
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