IndraLab
Statements
sparser
"An involvement of mTORC2 in calcium regulation in muscle is also supported by the decrease in the phosphorylation of calmodulin 1 (CALM1) in Ric mKO muscle, since
calmodulins are calcium ion sensor proteins that transduce most of the calcium signalling to downstream protein kinases and phosphatases (Marcelo et al. 2016)."
sparser
"Furthermore, CSC (25 microgram/ml) both increases the rate of transendothelial migration of vitamin D3-differentiated monocyte-like cells across the HUVEC monolayer by 200% and causes an approximately 10-fold increases in the phosphorylation of platelet endothelial CAM (PECAM-1), an adhesion molecule located at intercellular junctions and involved in endothelial cell-cell adhesion."
sparser
"All
reactions were monitored by thin layer chromatography (TLC) carried
out on either Merck silica gel plates (0.25 mm thick, 60F254) or Millipore
Silica gel aluminum sheets (60F254) and visualized by using UV (254
nm) or dyes such as KMnO 4 , p -anisaldehyde,
and CAM (Hannesian’s Stain)."
sparser
"The current understanding of the exact pathophysiological mechanism and how it links to the structural components of calmodulin structure is not clear, however, it is likely related to the large sarcoplasmic Ca 2 + release channel RyR2 sharing the same phenotypic expression.[ xref ] Proof of concept studies using knock-in animal models and human-induced pluripotent stem cells are missing and are another area of research.[ xref ] A recent study making use of nuclear magnetic resonance was able to provide insight into the particular structural effects of CALM1 p."