IndraLab

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PKC inhibits KCNQ5. 4 / 4
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"These results suggest that despite its ability to directly activate TRPC6 channels (XREF_SUPPLEMENTARY), DAG contributes to the stimulation of Ca 2+ spiking primarily via PKC dependent suppression of KCNQ5 currents."
19246091
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"We previously provided evidence that physiological concentrations (10-100 pM) of AVP indeed produce membrane depolarization and Ca 2+ influx in A7r5 rat aortic smooth muscle cells through a protein kinase C (PKC)-dependent suppression of KCNQ5 currents [XREF_BIBR]."
19246091
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"These results suggest that the stimulation of Ca (2+) spiking by physiological concentrations of AVP involves PKC dependent inhibition of KCNQ5 channels and increased AP firing in A7r5 cells."
17071736
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"We previously provided evidence that physiological concentrations (10-100 pM) of AVP indeed produce membrane depolarization and Ca 2+ influx in A7r5 rat aortic smooth muscle cells through a protein kinase C (PKC)-dependent suppression of KCNQ5 currents [XREF_BIBR]."
19246091