IndraLab

Statements

Phosphorylated STAT3 increases the amount of HIF1A. 5 / 5
| 5
reach
"Indeed, STAT3 phosphorylation increases expression of HIF1alpha by inhibiting HIF1alpha degradation in tumor cells [XREF_BIBR]."
29518129
reach
"The MEK and ERK MAPK pathway drives STAT3 (pS727) activation, and the c-KIT/PI3K/AKT/mTOR pathway induces STAT3 (pS727) phosphorylation, leading to expression of IDO and HIF-1alpha."
26343197
reach
"Meanwhile, the phosphorylation and activation of STAT3 could increase the transcription of HIF1A , encoding a hypoxia-inducible factor related to cytotoxic damage."
36674945
reach
"Serotonin (5-HT) phosphorylates Jak1, resulting in the phosphorylation of STAT3 which promotes ERK1/2 activation, Akt phosphorylation and HIF-1a expression (68) ."
34759927
reach
"Pre-treatment with soy isoflavones inhibits radiation induced Src and STAT3 phosphorylations and radiation induced HIF-1alpha expression in PC-3 cells."
19101986