IndraLab

Statements


USP10 activates HDAC6 protein. 2 / 2
| 2

eidos
"The above results suggest that USP10 up-regulates HDAC6 protein expression , most likely through deubiquitinating and consequently stabilizing HDAC6 ."

eidos
"As shown in Fig.3a , knockdown of USP10 decreased HDAC6 protein levels as compared to the control H23 cells , while MG132 restored HDAC6 expression in the knockdown cells , indicating that blocking proteasome degradation leads to HDAC6 accumulation ."