
IndraLab
Statements
eidos
"Low levels of USP26 degrade drosophila mothers against decapentaplegic protein 7 ( SMAD7 ) and stabilize TGFbeta , while high levels of USP26 stabilize SMAD7 by deubiquitylation and form a complex with SMAD ubiquitylation regulatory factor 2 ( SMURF2 ) , which degrades the TGF-beta receptor by ubiquitylation [ 34 ] ."