IndraLab

Statements

USP30 binds Lys6 and monoubiquitin. 2 / 2
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"Here we report crystal structures of human USP30 bound to monoubiquitin and Lys6 linked diubiquitin, which explain how USP30 achieves Lys6-linkage preference through unique ubiquitin binding interfaces."
28945249
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"Encouragingly, the crystal structure of human USP30 bound to monoubiquitin and Lys6-linked di-ubiquitin was reported recently , providing insights into the activity and regulation of USP30 to facilitate drug design against this enzyme."
33890401