IndraLab

Statements


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sparser
"We examined the importance of this binding site in the feedback phosphorylation of MEK1 on Thr(292) and Thr(386) by ERK2, the phosphorylation and activation of ERK2 by MEK1, and the interaction of MEK1 with ERK2 and Raf-1."

sparser
"To identify arrestin-2 elements involved in the binding of c-Raf1, MEK1, and ERK2 we generated 22 mutants in which residues conserved between non-visual arrestins on the non-receptor-binding surface were replaced with alanines individually or in groups ( xref , xref )."

sparser
"In addition, there were 41, 35, and 31 pathways associated with MAPK1, MAP2K1, and RAF1, among which, MAPK signaling pathway (hsa04010), chemokine signaling pathway (hsa04062), and Focal adhesion (hsa04510) were the most closely related ones."

sparser
"The effect of arrestin-2 and arrestin-3 binding to the β2-adrenergic receptor on its interactions with c-Raf1, MEK1, and ERK2 in cellular environment."

sparser
"Expression of PEBP1 results in production of phosphatidylethanolamine-binding protein 1, a protein that in humans has been shown to interact with C-Raf, MAP2K1 and MAPK1 [ xref ]."

sparser
"MEKK1, an important regulator in stress- and cytokine-induced JNK/SAPK pathways, has also been implicated in the activation of ERK1/2 (Minden et al., 1994; Xu et al., 1996; Yujiri et al., 1998) and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"