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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

NFkappaB activates OTUD4. 1 / 1

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"OTU deubiquitinase 4 (OTUD4) is a member of OTD deubiquitinase (DUB) family, which participates in various physiological and pathological processes, such as embryonic development of zebrafish, repair of DNA alkylation damage, and innate immune response ( xref ; xref , xref ; xref ). xref revealed that OTUD4 negatively modulated TLR-mediated NF-κB activation and silencing of OTUD4 increased the phosphorylation of p38 MAPK upon the stimulation of IL-1β."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...