IndraLab

Statements


IL1B increases the amount of CD4. 3 / 3
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"Conversely, neither LPS nor TNF-alpha and IL-1 beta were able to modulate surface CD4 expression on quiescent or phytohaemagglutinin (PHA)-activated lymphocytes."

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"However, after 24h, IL-1beta significantly increased surface expression of the positive CD4 + T-cell co-stimulatory molecule, ICOS-L 57."

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"This down-regulation of CD4 expression by LPS, TNF-alpha, and IL-1 beta occurs at the level of transcription."