IndraLab

Statements


SPATA2 binds CYLD and USP domain. 3 / 3
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"Consistently, other studies reveal CYLD interacts with SPATA2 via the USP domain, supporting the notion that USP domain might also be a critical element for protein protein interactions [XREF_BIBR, XREF_BIBR]."

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"SPATA2 binds the USP domain of CYLD via its PUB domain, but in a PIM independent manner."

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"It has been shown that the USP domain of CYLD binds the PUB domain of spermatogenesis associated protein 2 (Spata2), leading to recruitment of CYLD to the centrosome and de-ubiquitination of Plk4."