IndraLab

Statements

Glu-Ala increases the amount of OTULIN. 3 / 3
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"EA treatment promotes OTULIN gene transcription and protein synthesis in the brain, and enhanced OTULIN expression was primarily located in neurons."
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"EA enhanced OTULIN expression following focal cerebral ischaemia and reperfusion injury."
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"EA also enhanced microglial OTULIN expression in the present study, and OTULIN silencing effectively reversed the inhibitory effect of EA on microglial activation, as shown by the increased mean Iba-1 immunofluorescence intensity, which strongly indicates that enhanced OTULIN expression is necessary for EA to alleviate microglial activation."
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