IndraLab

Statements


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"All together, these data clearly demonstrate that UCHL1 can downregulate the PRR mediated activation of both the type I IFN and proinflammatory cytokine and chemokine pathways."

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"To test whether hrHPV induced UCHL1 inhibits PRR signaling, we used lentiviral vectors expressing short-hairpin RNA (shRNA) against UCHL1 and this resulted in a downregulated expression of UCHL1 transcripts and protein levels in hrHPV+ KCs (XREF_FIG)."