IndraLab

Statements

CDKN2A methylates TP53. 5 / 5
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"Our study uncovered a novel aspect of the VHL-p53-ARF interaction, arginine methylation of p53 by VHL, ARF, and PRMT3."
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"20 In addition, the protein complex consisting of PRMT3, the von Hippel-Lindau (VHL) tumor suppressor protein, and ARF (alternative reading frame) methylates the tumor suppressor p53."
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"ARF and VHL30 promote p53 arginine methylation by PRMT3."
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"Overexpression of p53 and hypermethylation of CDKN2A (P16INK-4a) have been reported in OSD ."
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"There was no association between p16 hypermethylation of K-ras gene mutation, p53 overexpression and LOH of the DCC gene."
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