IndraLab

Statements

RNAi inhibits KCNH3. 2 / 2
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reach
"In double mutants of rab-7 with sorf-1 or sorf-2, RNAi depletion of vps-34, bec-1, or Y34B4a.2, which encodes the C. elegans homolog of UVRAG, strongly suppressed the enlargement of early endosomes in hypodermal cells (XREF_FIG)."
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reach
"Interestingly, we found that RNAi mediated inhibition of bec-1, lgg-1, vps-34, or the putative autophagy inducer pha-4 all significantly reduced the lifespan of LIPL-4 overexpressing animals, while having negligible effects on non transgenic siblings (XREF_FIG, and XREF_SUPPLEMENTARY)."
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