IndraLab

Statements

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"Here we could show that 5 muM MRT67307 completely prevented CYLD phosphorylation, while 1 or 2 muM reduced the phospho (Ser418)-CYLD signal only partially."
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"Moreover, CYLD phosphorylation was still inhibited by MRT67307 in IKKepsilon deficient cells."
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"Our observation that MRT67307 inhibits CYLD phosphorylation in IKKepsilon and TBK1 deficient cells indicates a role for other MRT67307 sensitive kinases in TCR signaling."
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"MRT67307 significantly decreased CYLD phosphorylation in wild-type cells."
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