IndraLab

Statements

Phosphorylated RPS6KB1 is active. 11 / 11
5 6 |
signor
"Erk phosphorylates multiple cytoplasmatic and cytoskeletal proteins, including mapk-activated protein kinases and the ribosomal p70-s6 kinase"
14967450
signor
"Erk phosphorylates multiple cytoplasmatic and cytoskeletal proteins, including mapk-activated protein kinases and the ribosomal p70-s6 kinase"
14967450
signor
"Erk phosphorylates multiple cytoplasmatic and cytoskeletal proteins, including mapk-activated protein kinases and the ribosomal p70-s6 kinase"
14967450
signor
"Here we report that ribosomal protein S6 kinase beta 1 (S6K1), a member of AGC kinases and downstream target of mechanistic target of rapamycin complex 1 (mTORC1), directly phosphorylates PDK1 at its pleckstrin homology (PH) domain, and impairs PDK1 interaction with and activation of AKT."
35318320
signor
"Protein phosphatase 2a inactivates the mitogen-stimulated s6 kinase from swiss mouse 3t3 cells"
2826472
signor
"Expression of WT-PTEN also caused decreased activation of Akt, p70 S6K, and Erk signaling pathways.|This may potentially be a result of PTEN inhibition of p70 S6K phosphorylation and may explain the mechanism by which PTEN inhibits proliferation of HSCs."
19436944
biopax:pid
No evidence text available
16611854
biopax:pid
No evidence text available
9162082
biopax:pid
No evidence text available
7528328
biopax:pid
No evidence text available
7760801
biopax:pid
No evidence text available
1614535