IndraLab

Statements

Doxycycline inhibits USP11. 2 / 2
| 2
reach
"Supporting this, the addition of MG132 only marginally increased PRMT1 ubiquitylation (Supplementary Fig. 5a), whilst protein levels of PRMT1 in two different breast cancer cell lines were unchanged after doxycycline-induced depletion or overexpression of USP11 (Fig. 7e)."
34728620
reach
"Supporting this, doxycycline-inducible knockdown of USP11 and re-expression of methyl-deficient USP11 resulted in impaired clearance of 53BP1 foci in late S/G2 cells indicating persistent and unrepaired DSBs (Fig. 4c and Supplementary Fig. 2a)."
34728620