IndraLab

Statements

RPL11 binds RPL5, TP53, and MDM2. 5 / 5
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sparser
"Two ribosome proteins, RPL5 and RPL11, are major mediators of this Ribi checkpoint; excess RPL5 and RPL11 bind Mdm2 and inhibit its interaction with p53, causing p53 to accumulate ( Teng et al., 2013 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26165925
sparser
"Two ribosome proteins, RPL5 and RPL11 are major mediators of this Ribi checkpoint; excess RPL5 and RPL11 bind Mdm2 and inhibit its interaction with p53, causing p53 to accumulate ( xref )."
26165925
sparser
"Under conditions of defective ribosome biogenesis, this apoptotic response is triggered by the ‘nucleolar stress response’, the binding of excess ribosomal proteins, such as RPL5 and RPL11, to Mdm2, which in turn prevents Mdm2 mediated p53 degradation [ xref ]."
25756904
reach
"These results suggest that RPL4 may associate with the RPL5, RPL11, MDM2, and p53 complex."
26908445
reach
"RPL4 interacts with the RPL5, RPL11, MDM2, and p53 complex in cells."
26908445