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eidos
"In the in vitro deubiquitination assay , OTUD5 catalyzed the efficient deubiquitination of TRIM25 , and the TRIM25 deubiquitination required OTUD5 DUB activity , as indicated by the catalytically inactive OTUD5 ( OTUD5 / C224S ) failing to deubiquitinate TRIM25 ( Fig. 3b , c , lane 2 versus lane 5 ) ."