IndraLab

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VLX1570 binds UCHL5. 2 / 2

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"VLX1570 binds and inhibits the activity of USP14 and UCHL5."

27813535

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reach

"VLX1570 preferentially binds the Cys88 residue of UCHL5 and interfaces with a thiol of USP14 at residue Cys114 via a 1,4-Michael 's addition reaction, potentially forming a covalent bond."

27813535

INDRA sources:

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IndraLab

Statements

VLX1570 binds UCHL5. 2 / 2

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