IndraLab

Statements

SHC1 binds EGFR and GRB2. 5 / 5
1 | 4
sparser
"3.1 As 2 O 3 Induces EGFR and ShcA Phosphorylation and Interaction with Grb2 Adaptor Proteins in HEY Ovarian Carcinoma Cells."
23178716
sparser
"Increased binding of p66Shc to activated EGFR and Grb2 occurs during severe oxidative stress."
25890053
sparser
"It has been reported that after administration of a single receptor-saturating dose of EGF there is a rapid and extensive receptor internalisation with a concomitant tyrosine phosphorylation of 170- a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
9877160
sparser
"For instance, increased binding of GRB2 and SHC1 to EGFR was detected as early as 30 s, peaked at 2 min, and maintained with high intensity until 2 h (>60% of the maximal binding); in contrast, SOS1 and MAP4K3, which were also maximally detected at 2 min, were quickly dissociated as their amounts were decreased to <5% of the maxima by 30 min ( xref )."
31442056
hprd
No evidence text available
16729043