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EIF3H activates epithelial to mesenchymal transition. 3 / 3
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"We observed that disruption of EIF3H by RNA interference results in attenuation of EMT as indicated by upregulation of E-cadherin and suppression of vimentin as well as fibronectin, while elevation of EIF3H significantly enhances EMT phenotypes in breast cancer cells with dramatic alteration of morphology, loss of E-cadherin and accumulation of vimentin as well as fibronectin (XREF_SUPPLEMENTARY - XREF_SUPPLEMENTARY)."
eidos
"We observed that disruption of EIF3H by RNA interference results in attenuation of EMT as indicated by upregulation of E-cadherin and suppression of vimentin as well as fibronectin , while elevation of EIF3H significantly enhances EMT phenotypes in breast cancer cells with dramatic alteration of morphology , loss of E-cadherin and accumulation of vimentin as well as fibronectin ( Fig. S1G-J ) ."